Juan C. Landoni

Juan C. Landoni, Ph.D.

Mitochondria | Metabolism | Ageing | Microscopy

Curriculum Vitae

Professional Experience

Postdoctoral researcher

2022 - present

Laboratory of Experimental Biophysics (Prof. Suliana Manley), Institute of Physics, EPFL, Lausanne, Switzerland 🇨🇭

Fundamental mechanisms of mitochondrial genome organization and quality-control using advanced and super-resolution microscopy.

Doctoral researcher

2019 - 2022

Mitochondrial Medicine laboratory (Prof. Anu Suomalainen-Wartiovaara), Stem Cells and Metabolism, University of Helsinki, Finland 🇫🇮

Mitochondrial DNA maintenance disorders, metabolism, cardiac development, and aging.

Undergraduate researcher

2014 - 2019

Mitochondrial Medicine laboratory (Prof. Anu Suomalainen-Wartiovaara), Molecular Neurology, University of Helsinki, Finland 🇫🇮

Pathomechanisms of human genetic diseases affecting mitochondria and metabolism.

Education

Doctor of Philosophy (Ph.D.) in Integrative Life Sciences / Biomedicine

2019 - 2022

Faculty of Medicine, University of Helsinki, Finland 🇫🇮

Dissertation: Mitochondrial DNA replication defects: consequences for neonatal heart disease & premature aging

Master of Science (M.Sc.) in Translational Medicine

2017 - 2019

Faculty of Medicine, University of Helsinki, Finland 🇫🇮

Thesis: Structural Insights into Creatine Transport from Novel Disease Mutation

Bachelor of Science (B.Sc.), Chemistry

2014 - 2017

Faculty of Science, University of Helsinki, Finland 🇫🇮

Thesis: Development of a New Method for Quantitative dNTP Pool Measurement from Biological Samples

Languages

Spanish (Native)

English (Fluent, C2)

French (Fluent, C1-C2)

Teaching & Mentoring

Mentoring of students in the laboratory [English]

2018 - 2025

M.Sc. (5), M.D.-Ph.D. (2) and Ph.D. students (2, one faculty appointed co-supervisor)

University of Helsinki, Finland 🇫🇮 & EPFL, Switzerland 🇨🇭

Instructor | Molecular Biology, Cell Biology [French]

2023 - 2025

[French] Swiss Biology Olympiad IBO|Suisse, Switzerland 🇨🇭

Research facilitator | Physiology: Modern Cell Biology Using Microscopic,
Biochemical and Computational Approaches [English]

2024

University of Chicago Marine Biology Laboratory, Woods Hole, USA 🇺🇸

Instructor | Cell Biology & Methods in Molecular Biology [Spanish]

2025

Olimpíada Argentina de Biología, Argentina 🇦🇷

Organizer/presenter | Stem Cells and Metabolism Seminar Series [English]

2019 - 2021

University of Helsinki (Dpbm-158, scientific seminars and career skills and development workshops), Finland 🇫🇮

Mentor | Iberoamerican Biology Olympiad [English, Portuguese]

2017

Iberoamerican Biology Olympiad, Azores, Portugal 🇵🇹

Mentor/expert | Genome editing team, Millennium Youth Camp [English]

2014

Technology Academy Finland & Aalto University, Finland 🇫🇮

Mentor | Iberoamerican Biology Olympiad [Spanish]

2013

Iberoamerican Biology Olympiad, Rio Cuarto, Argentina 🇦🇷

Intercultural Education mentor/facilitator [English & Spanish]

2011 - 2018

AFS Intercultural Programs, Argentina 🇦🇷 & Finland 🇫🇮

Institutional & Academic Responsibilities

Faculty Council member

2023 - present

Faculty Council of the School of Basic Sciences , École Polytechnique Fédérale de Lausanne (EPFL), Switzerland 🇨🇭

Delegate

2023

International Workshop on Treatment of mtDNA Maintenance Disorders
(15-person clinician, scientist, patient relative, and pharma consensus meeting), The Netherlands 🇳🇱

Board member & International Tutoring Coordinator

2016 - 2017

Helsingin Yliopiston Kemistit ry (Student union for chemistry students at the University of Helsinki), Finland 🇫🇮

Outreach & Volunteering Activities

Grants, Fellowships and Awards

Cell Symposia in Multifaceted Mitochondria

2024

Best poster prize | Sitges, Spain 🇪🇸

EMBO Inter-organelle Contacts Biology

2023

Best poster prize | Fiuggi, Italy 🇮🇹

Global Young Scientist Summit (GYSS)

2023

Video Competition Winner | Singapore National Research Foundation, Singapore 🇸🇬

Faculty of Medicine, University of Helsinki

2022

Ph.D. dissertation distinction | Pioneering theses of exceptional quality, top 10% | Finland 🇫🇮

Faculty of Medicine Research Programs Unit Science Day 2022

2022

Best poster prize | Finland 🇫🇮

Orion Science Foundation

2022

Stipend [5 000 €] | "Enhanced mtDNA replication as a mechanism underlying neonatal heart failure"

Päivikki ja Sakari Sohlberg Foundation

2022

Materials grant [8 000 €] | "Enhanced mtDNA replication as a mechanism underlying neonatal heart failure"

Maud Kuistila Foundation

2021

Stipend [5 000 €] | "Enhanced mtDNA replication as a mechanism underlying neonatal heart failure"

Global Young Scientist Summit

2021

Selection | Singapore National Research Foundation, Singapore 🇸🇬

Alfred Kordelin Foundation

2020

Research visit grant [12 000 €] | "Dynamics of mtDNA Synthesis - Relevance for Infantile Muscle Diseases" | UC Davis, USA

University of Helsinki Funds

2020

Top-10 Ph.D. application salary position [~175 000 €] | Best 10 proposals across the university | Finland 🇫🇮

Doctoral Programme in Integrative Life Sciences

2020

Salary position [~175 000 €] (granted & declined) | Finland 🇫🇮

Doctoral Programme in Biomedicine

2020

Salary position [~175 000 €] (granted & declined) | Finland 🇫🇮

Päivikki ja Sakari Sohlberg Foundation

2020

Materials grant [8 000 €] | "Dynamics of mtDNA Synthesis - Relevance for Infantile Muscle Diseases"

Orion Science Foundation

2020

Stipend [5 000 €] | "Dynamics of mtDNA Synthesis - Relevance for Infantile Muscle Diseases"

Maud Kuistila Foundation

2020

Stipend [5 000 €] | "Dynamics of mtDNA Synthesis - Relevance for Infantile Muscle Diseases"

Faculty of Medicine Research Programs Unit Science Day 2018

2018

Best poster prize | Finland 🇫🇮

Faculty of Medicine Research Programs Unit Science Day 2017

2017

Best poster prize | Finland 🇫🇮

FASEB Folate, B12 and One-carbon Metabolism Conference

2016

Best poster prize | "Mitochondrial DNA replication disorders remodel one-carbon metabolism" | Steamboat Springs, Colorado, USA 🇺🇸

Faculty of Science, University of Helsinki

2014

Direct Admission Offer | Finland 🇫🇮

Millennium Youth Camp

2013

Selection | Competitive global selection of promising young students | Technology Academy Finland & Aalto University, Helsinki, Finland 🇫🇮

Talks at International Conferences

EMBO | EMBL Symposium: Seeing is believing: imaging the molecular processes of life

2025

Selected talk | "Pearling mediates mitochondrial DNA and microdomain distribution" | Heidelberg, Germany 🇩🇪

Cell Symposia in Multifaceted Mitochondria

2024

Selected talk | "Pearling mediates mitochondrial DNA and microdomain distribution" | Sitges, Spain 🇪🇸

Keystone Symposia on Mitochondria Signaling and Disease

2024

Selected talk | "Mitochondrial Pearling as a Putative Content Management Mechanism" | Banff, Canada 🇨🇦

Keystone eSymposia – Metabolic Decisions in Development and Disease

2021

Selected talk | "The Consequences of Increased mtDNA Replication: From Premature Aging to Neonatal Disease" | USA 🇺🇸

EMBO|FEBS Lecture Course Mitochondria in life, death and disease

2017

Selected talk | "A Genomic Non-Coding Complex Regulates Mitochondrial DNA Maintenance in CNS" | Bari, Italy 🇮🇹

FINMIT Mitochondria, Metabolism and Disease meeting

2017

Selected talk | "New Insights into Creatine Transport and Metabolism" | Tampere, Finland 🇫🇮

FASEB conference on folate, vitamin B12 and one-carbon Metabolism

2016

Selected talk | "Mitochondrial DNA replication disorders remodel one-carbon metabolism" | Colorado, USA 🇺🇸

Contact